璇佸埜涔嬫槦娑堟伅锛?024骞?鏈?5鏃ユ柊璇哄▉锛?00765锛夊彂甯冨叕鍛婄О鍏徃浜?024骞?鏈?5鏃ユ帴鍙楁満鏋勮皟鐮旓紝涓俊閲屾槀銆侀箯鍗庡熀閲戙€佷腑娆у熀閲戙€佸浗娉板悰瀹夈€丷BC銆佸伐閾剁憺淇″熀閲戙€丟IC銆乁BS銆佸崥鏃跺熀閲戙€佸缓淇″熀閲戙€佷笢鍚磋瘉鍒搞€佸崕娉拌瘉鍒搞€佸叴涓氳瘉鍒搞€佸浗淇¤瘉鍒搞€佺敵涓囧畯婧愩€佷腑閲戝叕鍙搞€佹姇璧勮€呫€佹懇鏍瑰+涓瑰埄銆佽礉鑾卞痉鍩洪噾銆佹嫑閾跺浗闄呫€佸痉閭﹁瘉鍒搞€佸崕澶忓熀閲戙€佷腑閾跺熀閲戙€佹眹娣诲瘜鍩洪噾鍙備笌銆?/p>
鍏蜂綋鍐呭濡備笅锛?/p>
闂細鏈閲嶇粍鐩殑鍜屾剰涔夈€?/strong>
绛旓細鏈閲嶇粍鍚庢柊璇哄▉浣滀负鐭宠嵂闆嗗洟鍦? 鑲″敮涓€鍒涙柊鑽钩鍙扮殑鎴樼暐涓庡竷灞€灏嗗緱鍒拌繘涓€姝ュ嚫鏄撅紝鏂拌濞佸皢鍔犻€熸墦閫犲浗鍐呴鍏堢殑鍒涙柊鑽笂甯傚叕鍙稿钩鍙帮紝鍏煎叿鐩堝埄鑳藉姏鍜岄噸閲忕骇鐨勭爺鍙戠绾垮拰骞冲彴锛岃嚧鍔涗簬鎴愰暱涓烘瀬鍏锋綔鍔涚殑浼樿川鍒涙柊鑽叕鍙搞€傛湰娆¢噸缁勬湁鍒╀簬鐭宠嵂闆嗗洟鍒涙柊璧勪骇鐨勯暱鏈熶环鍊煎彂鐜帮紝瀹炵幇 +H骞冲彴鍏卞悓鍙戝睍锛屾儬鍙婁袱鍦版姇璧勮€呫€?/p>
闂細鏈浜ゆ槗鏂规鎯呭喌銆?/strong>
绛旓細鏈浜ゆ槗鏂规锛屽垎涓轰袱閮ㄥ垎 绗竴閮ㄥ垎涓哄彂琛岃偂浠藉強鏀粯鐜伴噾璐拱鐭宠嵂鐧惧厠 100%鑲℃潈锛屽叾涓幇閲戞敮浠樻瘮渚嬩笉瓒呰繃 10%銆傝閮ㄥ垎涓嶅瓨鍦ㄥ悜绀句細鍏紬鍙戣鑲′唤鍙婅瀺璧勭殑鎯呭喌锛屽彂琛屽璞″凡纭畾涓虹煶鑽櫨鍏嬬殑鑲′笢缁寸敓鑽笟銆佹仼蹇呮櫘鑽笟鍙婄煶鑽紙涓婃捣锛変笁瀹跺叕鍙搞€傜洰鍓嶇煶鑽櫨鍏嬪叕鍙哥殑瀹¤璇勪及宸ヤ綔灏氭湭瀹屾垚锛屾殏鏃犳硶纭畾鍏蜂綋鐨勪氦鏄撳浠枫€傝閮ㄥ垎鑲′唤鐨勫彂琛屼环鏍煎強鍙戣鏁伴噺浜﹂渶娣变氦鎵€瀹℃牳鍚屾剰锛屽苟鎶ヨ瘉鐩戜細娉ㄥ唽鍚屾剰鍚庢柟鍙‘瀹氬疄鏂姐€?p/>绗簩閮ㄥ垎涓哄嫙闆嗛厤濂楄祫閲戯紝鏍规嵁璇佺洃浼氥€婁笂甯傚叕鍙搁噸澶ц祫浜ч噸缁勭鐞嗗姙娉曘€嬶紝涓婂競鍏徃鍙戣鑲′唤璐拱璧勪骇鐨勶紝鍙互鍚屾椂鍕熼泦閮ㄥ垎閰嶅璧勯噾锛屾槸娉曡璧嬩簣瀹炴柦璇ョ被閲嶇粍涓婂競鍏徃鐨勪竴椤规潈鍒┿€傛柊璇哄▉鏍规嵁娉曡瑕佹眰浠ュ強璧勪骇閲嶇粍鐨勯€氬父鍋氭硶锛屽湪鏈浜ゆ槗鏂规璁捐浜嗙浉鍏充簨椤规柟妗堬紝浣嗗叿浣撶殑鍕熼泦閰嶅璧勯噾閲戦鍙婂悗缁叿浣撳疄鏂芥儏鍐电洰鍓嶅潎鏈‘瀹氾紝灏嗘寜鐓х浉鍏崇洃绠¤姹傚強甯傚満鎯呭喌杩涜澶勭悊銆?/p>
闂細鏈浜ゆ槗鏍囩殑鐭宠嵂鐧惧厠浼板€兼按骞抽鏈熴€?/strong>
绛旓細鏈浜ゆ槗鏍囩殑鐨勮瘎浼扮粨鏋滃皢鍦ㄧ鍚堣瘉鍒哥洃绠℃硶瑙勮姹傜殑璧勪骇璇勪及鏈烘瀯鍑哄叿姝e紡璇勪及鎶ュ憡鍚庣‘瀹氥€傚叾浼板€煎畾浠峰皢鏄叕鍏佸悎鐞嗙殑銆傝祫浜ц瘎浼版満鏋勫皢渚濇硶鐙珛寮€灞曡瘎浼板伐浣滐紝鍚勬柟灏嗕笉浼氬共棰勮瘎浼板伐浣滃拰璇勪及缁撴灉锛岀‘淇濈粨鏋滅殑鍏厑鍚堢悊銆?/p>
闂細鐭宠嵂鐧惧厠 GLP-1 浜у搧鐨勬儏鍐点€?/strong>
绛旓細鐭宠嵂鐧惧厠 GLP-1 浜у搧澶勪簬鍦ㄧ爺鐘舵€佷腑锛孴G103 娉ㄥ皠娑诧紙鍒涙柊鍨嬮暱鏁堥噸缁勪汉婧愯儼楂樿绯栫礌鏍疯偨-1锛圙LP-1锛塅c 铻嶅悎铔嬬櫧锛夎偉鑳?瓒呴噸閫傚簲鐥囨鍦ㄨ繘琛?III 鏈熶复搴婏紝鍙哥編鏍奸瞾鑲芥敞灏勬恫锛堥暱鏁堣儼楂樼硸绱犳牱鑲?1锛圙LP-1锛夌被浼肩墿锛? 鍨嬬硸灏跨梾閫傚簲鐥囨鍦ㄨ繘琛?III 鏈熶复搴婏紝涓婅堪涓村簥鍦ㄧ爺浜у搧/閫傚簲鐥囬璁′粠2026 骞磋捣闄嗙画鑾锋壒涓婂競銆傛澶栨爣鐨勫叕鍙歌繕鏈夊寘鎷徃缇庢牸椴佽偨闀挎晥娉ㄥ皠娑诧紙娴佷綋鏅跺墏鍨嬶級銆佸徃缇庢牸椴佽偨鍙f湇鐗囧墏浠ュ強 GLP-1 鍙岄澏銆佷笁闈朵骇鍝佺瓑涓村簥鍓嶉樁娈电殑浜у搧甯冨眬銆備笂杩颁俊鎭凡鍦ㄩ妗堜腑鎶湶銆?/p>
闂細鐩墠宸ㄧ煶 EGFR -ADC 鐨勮繘灞曘€?/strong>
绛旓細EGFR -DC 鐩墠鍦ㄧ編鍥藉拰涓浗鍚屾椂杩涜 1 鏈熶复搴婂墏閲忛€掑鐮旂┒锛涘湪涓綆鍓傞噺缁勫凡缁忚瀵熷埌鑲跨槫缂╁皬鍜屽瑙傜紦瑙e弽搴旓紝灏氭湭鍙戠幇鍓傞噺闄愬埗鎬ф瘨鎬э紙DLT锛変簨浠跺彂鐢熴€傜洰鍓嶈€冭檻涓綆鍓傞噺缁勬墿灞曘€?/p>
闂細鏈潵鏂拌濞佹敹鍏ヨ妯$殑灞曟湜銆?/strong>
绛旓細鍥犵洰鍓嶅浜庨噸缁勮繃绋嬩腑锛屽彈閲嶇粍鐨勫畬鎴愭儏鍐电瓑浼楀鍥犵礌褰卞搷锛屾殏鏃犳硶杈冧负鍑嗙‘棰勮鐩稿叧鏀跺叆銆傜洰鍓嶅伐浣滃皢涓昏鑱氱劍浜庡湪鐮旂绾跨殑鐮斿彂/涓村簥寮€鍙戯紝濡傜爺鍙戠绾夸腑鐨勯噸鐐逛骇鍝丒GFR-DC銆丷SV 鐤嫍闇€鍔犲揩鐮斿彂杩涘害锛屽姏浜夋棭鏃ヨ幏鎵癸紝璐$尞鏀跺叆銆?/p>
闂細鏈浜ゆ槗鏄惁闇€瑕佹柊璇哄▉鍙紑鑲′笢澶т細銆?/strong>
绛旓細鏂拌濞侀渶鍙紑鑲′笢澶т細锛屾帶鑲¤偂涓滈伩琛ㄥ喅銆?/p>
闂細鏂拌濞侀渶瑕佹惌寤鸿嚜宸遍攢鍞洟闃熷悧銆?/strong>
绛旓細鑲′笂甯傚叕鍙搁渶淇濇寔涓氬姟銆佽祫浜с€佷汉鍛樸€佽储鍔°€佹満鏋勨€滀簲鐙珛鈥濓紝濡傞噸缁勫畬鎴愶紝閿€鍞洟闃熶汉鍛樺皢浼氶殢鐭宠嵂鐧惧厠绾冲叆鏂拌濞侊紝鐙珛杩愯惀銆備絾鍏跺晢涓氬寲鑳藉姏涓嶄細鍙楀埌浠讳綍褰卞搷銆?/p>
鏂拌濞侊紙300765锛変富钀ヤ笟鍔★細澶у仴搴烽鍩熷姛鑳介鍝佺殑鐮斿彂銆佺敓浜т笌閿€鍞€?/p>
鏂拌濞?023骞翠笁瀛f姤鏄剧ず锛屽叕鍙镐富钀ユ敹鍏?9.02浜垮厓锛屽悓姣斾笂鍗?.46%锛涘綊姣嶅噣鍒╂鼎5.83浜垮厓锛屽悓姣斾笂鍗?2.74%锛涙墸闈炲噣鍒╂鼎5.76浜垮厓锛屽悓姣斾笂鍗?5.66%锛涘叾涓?023骞寸涓夊搴︼紝鍏徃鍗曞搴︿富钀ユ敹鍏?.92浜垮厓锛屽悓姣斾笅闄?.08%锛涘崟瀛e害褰掓瘝鍑€鍒╂鼎1.83浜垮厓锛屽悓姣斾笅闄?.52%锛涘崟瀛e害鎵i潪鍑€鍒╂鼎1.82浜垮厓锛屽悓姣斾笂鍗?6.15%锛涜礋鍊虹巼8.63%锛屾姇璧勬敹鐩?81.23涓囧厓锛岃储鍔¤垂鐢?6254.39涓囧厓锛屾瘺鍒╃巼46.76%銆?/p>
璇ヨ偂鏈€杩?0澶╁唴鍏辨湁2瀹舵満鏋勭粰鍑鸿瘎绾э紝涔板叆璇勭骇2瀹讹紱杩囧幓90澶╁唴鏈烘瀯鐩爣鍧囦环涓?6.4銆?/p>
浠ヤ笅鏄缁嗙殑鐩堝埄棰勬祴淇℃伅锛?/p>
铻嶈祫铻嶅埜鏁版嵁鏄剧ず璇ヨ偂杩?涓湀铻嶈祫鍑€娴佸叆3.6浜匡紝铻嶈祫浣欓澧炲姞锛涜瀺鍒稿噣娴佸嚭343.21涓囷紝铻嶅埜浣欓鍑忓皯銆?/p>
浠ヤ笂鍐呭鐢辫瘉鍒镐箣鏄熸牴鎹叕寮€淇℃伅鏁寸悊锛岀敱绠楁硶鐢熸垚锛屼笌鏈珯绔嬪満鏃犲叧銆傝瘉鍒镐箣鏄熷姏姹備絾涓嶄繚璇佽淇℃伅锛堝寘鎷絾涓嶉檺浜庢枃瀛椼€佽棰戙€侀煶棰戙€佹暟鎹強鍥捐〃锛夊叏閮ㄦ垨鑰呴儴鍒嗗唴瀹圭殑鐨勫噯纭€с€佸畬鏁存€с€佹湁鏁堟€с€佸強鏃舵€х瓑锛屽瀛樺湪闂璇疯仈绯绘垜浠€傛湰鏂囦负鏁版嵁鏁寸悊锛屼笉瀵规偍鏋勬垚浠讳綍鎶曡祫寤鸿锛屾姇璧勬湁椋庨櫓锛岃璋ㄦ厧鍐崇瓥銆?/p>